Re-assessing gallium-67 as a therapeutic radionuclide

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Re-assessing gallium-67 as a therapeutic radionuclide☆

INTRODUCTION Despite its desirable half-life and low energy Auger electrons that travel further than for other radionuclides, 67Ga has been neglected as a therapeutic radionuclide. Here, 67Ga is compared with Auger electron emitter 111In as a potential therapeutic radionuclide. METHODS Plasmid pBR322 studies allowed direct comparison between 67Ga and 111In (1MBq) in causing DNA damage, includ...

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Cerebral Infarction Demonstrated by Gallium-67-Gallium Citrate Scintigraphy

Received 7/15/2009; revised 7/31/2009; accepted 7/31/2009. For correspondence and reprints contact: Shih-Chuan Tsai, M.D., Department of Nuclear Medicine, Taichung Veterans General Hospital. 160 Section 3, Taichung Harbor Road, Taichung 407, Taiwan. Tel: (886)4-23592525 ext. 4801, Fax: (886)423741348, E-mail: [email protected] We present the case of a 62-year-old man experiencing persistent f...

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Gallium-67 scintigraphy in polymyalgia rheumatica.

A patient with atypical presentation of polymyalgia rheumatica is presented. Her major symptoms were mild weakness, pain on passive movement of the shoulder and hip girdles, with mild tenderness but no joint stiffness. Muscle enzymes were within the normal range. The diagnostic work-up included gallium-67 scintigraphy, which showed intense uptake in both shoulders, with remarkable improvement f...

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Gallium-67 scintigraphy in macrophagic myofasciitis.

OBJECTIVE To evaluate gallium-67 (67Ga) uptake and the value of 67Ga scintigraphy for diagnosis of macrophagic myofasciitis (MMF), a recently identified inflammatory myopathy. METHODS Twelve consecutive patients with MMF confirmed by muscle biopsy, 10 with polymyositis, 10 with sarcoidosis, 8 with fibromyalgia, and 10 with lymphoma without muscle symptoms (serving as normal controls for muscl...

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Gallium-67 scintigraphy in lung diseases.

There is some disagreement in the literature about the tumour affinity and tumour specificity of gallium-67 (6VGa). The present investigation showed good uptake of 67Ga in most cases of bronchial carcinoma, but some uptake of 67Ga was also found in 30% of those with non-malignant lung lesions. There was no relationship between the uptake of 17Ga and the histo-logical type of bronchial carcinoma...

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ژورنال

عنوان ژورنال: Endocrine Abstracts

سال: 2016

ISSN: 1479-6848

DOI: 10.1530/endoabs.47.oc25